Las Vegas is filled with places that claim to be the "best steakhouse in town". As a matter of fact, just about every steak serving establishment can lay claim to winning some "best" award from one publication or another at some point. While I have yet to try out some of the newer acclaimed places like Carnevino or Strip House, my sense is that those places are overly trendy and noisy. That's why I like Charlie Palmer Steak. Located at the Four Seasons Hotel, attached to the Mandalay Bay, Palmer's is clubby, quiet and refined. This is not for the normal Vegas party crowd. Have a well-crafted cocktail (perhaps a Sidecar or ice cold vodka martini) in the lounge and prepare yourself for an excellent experience. Service is exceptional, always nearby but never hovering. I have eaten here half-a-dozen times or more, and the 20oz NY shell steak is my favorite. Get it with a side of wild mushrooms and the truffle twice-baked potato. Heaven.
The wine list is very deep, sharing the same cellar as sister restaurant Aureole upstairs. Desserts are OK, nothing to write home about.