Everything about this place just screams COOL! The beer is DELICIOUS. The samples are plentiful. The people who work there are friendly. A few more specific things I love about East End:
1) Prices for kegs are awesome. $60 for a sixtel--be still my heart! (But be sure to bring a check for the keg and tap deposit.)
2) If you bring a sixtel of Monkey Boy to a party where you know very few people, you are guaranteed to become the most popular person at the party. This is a fact.
2) They're active on twitter, and will always answer tweets. In fact, last time I wanted to reserve a keg, I just tweeted at them!
3) But keg reservations aren't always necessary. Just ask if they have any available when you get there.
This is my favorite microbrewery I've ever visited, and I'm not even a Pittsburgher! My boyfriend and I even own East End pint glasses (a Christmas gift from an awesome aunt and uncle) and tshirts (his: Big Hop; hers: generic East End logo tee).