I went with some friends for the first time, not expecting it to be wonderful but just something kind of fun and trashy to do in Vegas.
First, book ahead of time if you can. We booked our seats about a week out and there weren't many seats left to choose from.
Second, while there isn't really a bad seat in the house, if you are in the back or on the sides expect to be ignored. The guys came off the stage and danced and did stuff with girls but only in the middle section. We were in no-mans-land on the side. :( That felt kind of crappy. They should at least dance around the back too.
Third, get a picture after but expect to pay a lot. The gift shop is WAY overpriced, too.
The jello shots are fun and the guys are SUPER HOT. They do not disappoint. Overall it was a really fun show!