As an avid concert goer, I've visited many of the venues in the greater Charlotte area. Amos' is in my top 5. It is a standing room only venue with general admission tickets, so if you want an up close view to one of your favorite performers, get there before everyone else and you're golden. There's really not a bad seat in the place though. There are 2 huge full bars on the lower level so it's not hard to get your swerve on. I feel like the majority of their shows are along the classic rock/rock/alternative/metal lines, so if you're down with that definitely check out their calendar on their website to see who's coming soon. If you're like me and not particularly into that genre, they still have other genres perform there. I've seen Yelawolf and Chiddy Bang here. Both great shows.
I will say that I do prefer the Fillmore to this location in terms of appearances, but Amos' makes up for it with generally cheaper tickets.
There is an upper level as well that can provide patrons with an elevated view of the stage above everyone else.