Agh! I'm so torn on this one.
Absolutely one of the more unique places to eat in Pittsburgh. BYOB with no corkage, extremely friendly staff/ownership, eclectic mix-match of furniture and fixtures, very reasonable food prices (read ~$20 for an app and two entrees) and definitely an extremely laid back atmosphere.
The owners are fantastic and are eager to share their traditions with you, including pronunciation of the menu items, cultural norms (i.e. not providing the check prior to a guest asking for it), etc. They also were obviously eager and excited to have new customers come in.
Where Isis fell short on expectations was the food itself. While the menu has a great mix of options (small plates, sandwiches, and more traditional entrees), nothing really stood out in our meal. Not to say it was bad (I'll definitely be going back), but I wasn't left with that insatiable feeling of wanting more once I was done.