This store is right across the street from the place I used to work; as a result, I started shopping here pretty regularly to pick up groceries on the way home.
Like other people have pointed out, it is a fairly expensive grocery store compared to a lot of other locations. However, I have severe allergies- to the point where it makes food that I can eat very difficult to find at other grocery stores. Whole Foods is one of the few places I can come and regularly pick up a wide variety of ingredients that won't kill me. I have to avoid the nut section like the plague, but it's totally worth it.
Bonus: The staff is super friendly and always willing to help. Plus, the prepared foods section is delicious! They also have some pretty nice craft beers that I'll grab on occasion.