I have been to Fat Head's several times and it is my go to place for when I have company in Cleveland from out of town.
The building is huge, as well it should be, because it use to be a farmers market and they give tribute to this with a wall of pictures and a small history.
Fat Head's is foremost a brewpub. When you work through the front door the first thing that hits you is the smell of the hops and mush from the brew process. The large bar is on the left with plenty of room to sit and have a drink or two, maybe three.
This place is great for large parties, as they have massive tables that easily seat 10 or more people with plenty of room. The menu is large as well, with something for everyone. They have their signature headwich, which is simply a large sandwich that is one of the best I have ever had. If you plan on getting a salad be warned that they are also massive. Everything about this place pays tribute to the name Fat Head's because everything is so large and it will go to head as one of the best places to eat in Cleveland.