A newer version of the Venetian next door, the Palazzo features cozy, super-sized hotel rooms that have a "sunken" living room/sitting area and a core sleeping area, each with its own TV, as well as large, immaculate bathrooms with both shower and soaking tub. Given that the living room has a huge sofa of its own, you could conceivably stuff up to 4 people in a single room and still have breathing space to spare.
The views can be especially glorious if you're on a high floor with a view of the Strip, and the overall feel is comfortably but accessibly high-end. The gym is compact but decently equipped, and service and security were quite decent. All in all, a very pleasant way to relax and decompress from the hustle bustle of the Strip.