I'm a pretty big fan of Urban Outfitters, mostly because you never expect to find just about anything in there, but you always can, as long as you are willing to pay for it. I've found household items, cute chandeliers, and usually always get key covers there.. this past time it was unikeys :)
I sometimes cry a bit that the clothing is a little more mainstream than the other items, but I typically find a few basic pieces I should grab.
One awesome upside is the bags are durable and the straps long enough you can put the bag over your shoulder like a tote.. and the inside is bright pink.
Downfall is shoes are way too expensive there... I hate paying so much for things that just walk on the ground. Gross.
Not enough good deals or original clothing to go back frequently but I do love to window shop there and occasionally come out with a gem.