After the Star Trek Experience, we stopped in for drinks. There was a wedding reception that day, so the lone Borg on the floor spent his time chaperoning guests where they needed to go, and never stopped by our group. (Appropriately, it was a themed wedding. Comically, the guests were anything BUT Trek characters; it was cool seeing Darth Vader - escorted by two troopers - and a guy with an Alien popping out of his chest walking around.)
Wasn't a fan of the standard employee uniform: bowling shirts with "Quark's" emblazoned on. Our bartender was pretty blah, and not terribly present, amazing considering how empty it was (though it was the afternoon and this spot is off the Vegas strip).
The themed menu was annoying, as one can only read bad puns for so long before getting disgusted. Prices were so-so, beer being cheaper than hard liquor, as expected. Took a "Cardassian" shot which was tasty but not too potent, since it seemed to be only a small sampling of a drink.
I want to like Quark's, but the lack of service, attention, and creativity during my time there make them hard to recommend. However, your mileage (hopefully) will vary.