By far, the Venetian and the Palazzo are the best hotels on the strip. The Wynn is up there but you just cant beat a suite. The rooms are perfect for any type of party because they're so big.
For all you college kids who still like to pack 10 people in one room....go to the Venetian or Palazzo. Plenty of floor space for your sleeping bags. (come on, who hasnt done this yet?) Just dont look obvious walking to your room with a bunch of sleeping bags and pillows....
The service is the best. They have poker tournaments going on 24hrs, a huge sportsbook, ton of tables (though high limits), and of course some of the best looking waitresses.......drool.....