I went to a lot of shows here back when I was a teenager. This was before I moved to Toronto and I didn't know much about the city, so I used to think Lee's Palace was the centre of it all. I saw some pretty memorable shows that left a lasting impression on my youth.
These days my musical tastes have changed since the mid-90s. Lee's Palace definitely caters towards the indie rock crowd so since I moved to the city (ten years ago) I have only been back to Lee's a handful of times. They've thankfully changed the layout and moved the bar to the very back of the club along the wall, eliminating a dead zone and creating much more space for concert goers.
Even though I am only there about once-a-year, I've usually always had a good time at Lee's Palace and have seen many great shows. Plus it's a nice mid-sized venue right in the heart of the Annex, so you don't have to head out into the middle of nowhere to see quality headliners.