This review is for The Deuce & The SDX from Fremont St. Experience to the Strip:
Very convenient access from Fremont St. Experience downtown all the way to Mandalay Bay. Runs every 15 min. 24/7. Only drawback is it takes a bit of time & can get very crowded. But I guess it's the price you pay for not a lot of $ (i.e. vs. taxi or car rental). No drunken revelers seen during my visit but then again I only used the Deuce during the day when it's still early.
The Deuce bus stop begins at Neonopolis/Heart Attack Grill & ends at Mandalay Bay. OR you can catch the SDX by Binion Hotel which is supposed to have shorter stops & end at the South Strip Transfer Terminal which is just after L.V. Premium Outlet South. The SDX only stops at certain hotels along the strip so it's best to refer to the bus map, normally at the bus stop. If you catch the SDX later in the day it might be crowded with people who shopped at L.V. Premium Outlet North where the line begins, so you may have to stand all the way from downtown to the Strip.
Also, on the SDX you can enter from the back doors w/o showing your pass. I don't know what the fine is if you try to board without a pass & I wasn't about to find out. They do have monitors who check before boarding at some stops but not all.
It's very amusing to note that on almost every ride back to downtown, people were asking about directions to Pawn Stars. I only know you get off at Bonneville Transit Center and walk a couple blocks toward L.V. Blvd. The bus drivers will explain how to get there. It's kind of in a scary neighborhood so good luck if you go.