Good Bottle has a solid selection of local NC beers for sale. Even better, the staff is knowledgeable and helpful. One guy walked around with me and pointed out all the local sours. By the time I left about 20 minutes later, I was carrying a huge box and had spent over a hundred bucks.
They carry the likes of Wicked Weed, Westbrook, and Burial, but also lots of lesser-known names. There are also taps in the back for drinking in, and it's tied to a coffee shop area up front. For beers, I paid at the back register.
If you don't have time to stop at individual breweries, this is definitely a good "one-stop shop" type of place in Charlotte.