This is a must-stop every time I go to Vegas. It's designer discount heaven. But even outside of that (because a purse discounted to $300 from $900 is still $300), they have normal store outlets that can score you some killer deals. I walk away with at least two bags at every visit.
Hit up: J Crew, Banana Republic, Gap, Coach, Kate Spade, Juicy, Levis & Perry Ellis.
Pass on: Burberry. While I can appreciate a good deal, you just won't find it there. At least, I haven't!