This is the only consignment shop I visit. It's conveniently located next to my favorite local Trader Joe's, so I tend to stop by when I'm on a grocery mission.
It's a fun place to spend a lot of time browsing. You really need to take your time there before finding something that works. It's hit or miss with fashion finds, but I'm a fan overall.
Among the coolest things I've scored: tweed pencil skirt, DKNY sweater and a massive Smokey Quartz cocktail ring set in sterling silver. God, I love that ring and it was only $15.
When I first started shopping there a year ago, they took a lot of my gently used or new designer duds. Lately (probably given the economy), they are taking less of my stuff. I'm guessing they are getting fancier items as more people are getting desperate. I notice they almost always accept designer jeans.
Clothes are arranged by color, which is interesting. Great for finding skirts, jewelry and bags. Wouldn't recommend getting your basic shirts or shoes there, better deals are often found at my local T.J. Maxx, Marshall's or even Nordstrom Rack.