Uh.mazing. I've eaten at almost every "top" restaurant in Pittsburgh, including most of the ones from Pittsburgh Magazine's "Top 25 Restaurants" list for 2012. The only reason I gave it 4 was because service was a little slow. Other than that, the food was amazingly good (and well worth the wait) and fresh.
I had the chicken dish with portobello mushrooms in a sherry wine sauce, lemon asparagus, and mashed red potatoes. The chicken was very tender, juicy, and flavorful. The potatoes were incredibly fresh and creamy with the skin on too. The asparagus was good, but not wow (how 'wow' can asparagus be?).
My husband had a meat dish - I think he ordered the tenderloin - and he said it was amazing. I tried it as we'll and it was delicious. He ordered it medium and it was cooked exactly as he had asked. Juicy, flavorful. No complaints. It was also served with fettuccine Alfredo. I honestly would order his dish just for the fettuccine alone. So. Freakin'. Good.
They have a great wine selection including a list of 25 wines for $25. The total bill came to $85.00 (excluding tip) and was worth every penny.
I recently went to Eleven in the Strip District and paid almost $200 (excluding tip) and thought it paled in comparison to Luma. If there were half stars I would have given it 4.5. Go. Now. Don't. Wait!