If you're looking for a large beer selection (and good food), The Urban Tap is your best bet in South Side. Their draft list is extensive, and always has something new to try. And, their bar tenders are generally knowledgeable and friendly.
In addition to drinking at the bar, I've sat down to eat here twice. Both times were decent; the food is good but a little pricy. However, if you get a good server it's an altogether pleasant experience.