Meat & Potatoes gets a lot of hype on the Pittsburgh brunch scene, it is good, it's nice, and sometimes it's excellent but not always.
The ambience is great, but this is not the cleanliest place. Last visit I was disappointed at the amount of crumbs I sat in upon getting to the table. I was next to the window sill which had a nice thin layer of dust.
I don't have any complaints about the service, the staff has always been friendly. The restaurant is always busy (good for them!) so I've never gotten the feeling of service that went above and beyond, and some servers are more knowledgable on the menu than others, but they are nice and they get the job done.
If you've never been, I say go! Check it out, and hopefully your visit is a great one.