The Skinny: even though this is the smallest selection compared to the other Whole Foods, it has the best in-store specials and samples. The service is generally better with friendlier cashiers.
Even though the West Charleston location is closer to my home, I will trek it out here to shop at this Whole Foods too. I usually do a package deal - I hit Trader Joe's on Buffalo and this store in one go because they are just so close to one another.
Why do I come here?
Yes, this place is tiny compared to the other Whole Foods. However, I must say the in-store specials are better at this store than at the Charleston location and are easier to find due to the size of the store. I have found their baking section has a different selection (again smaller) than their other counterpart. Their meat and seafood department is substantially smaller so I usually do not make my meat purchases here.
I find it is easier to shop here - I don't find myself roaming through the endless aisles, looking for stuff. I really do appreciate the fact that I can get in and get out quickly without too much fuss.
After perusing the deli section, I think that theirs is nicer than the Charleston location even though it is smaller. Let's face it - a lot of the time, the Charleston location is so picked over. The Lake Mead deli area is clean and they have a different selection compared to what is available at the other store.
So in short, both locations appeal for different reasons.