I hate to write a negative review of a place so critically acclaimed, but Twist was a colossal FAIL for us. We went there based on the extremely high recommendation posted on uhockey's blog. The hotel itself is very cool. It's dark and the bar had spectacular floor to ceiling windows on each side. The restaurant was completely empty on a Tuesday night which was a bad sign. We opted for the "Spirit" tasting menu with wine pairings. Only 2 of the courses were really good (the scallop with pumpkin soup and the venision). The remainder were either not memorable or literally downright inedible. Things tending to be on the extreme cold or bitter side (or both). The "Iichiko" course was downright disgusting. When we all complained to the waiters about it they laughed at us (as if the joke was on us).
Even if you don't believe the negative reviews and want to try Twist anyway, be away that this place is uber-expensive. 2 tasting menus with wines (and not even the fancy wines) is about $750! This was over double what it cost us to eat at far better and fancy restaurants in Vegas. Overall, Twist is extremely overrated and disappointing.