Stayed at the D for Life is Beautiful 2016. The hotel is in a great location to all Downtown Las Vegas destinations. It's right on Fremont Street and about two blocks from the main entrance to the Life is Beautiful event. The D was about a $20 Lyft ride from the airport.
We had a room on the 9th floor facing the 4 Queens and one of the Fremont Street Experience stages. Rooms were clean and relatively well furnished. I'd say Holiday Inn 2.0 decor. What's unfortunate at times is the noise. If you are facing Fremont, expect to hear loud music well into the 1 a.m. to 2 a.m. time frame. It didn't really bother us that much b/c we came back from the festival pretty late, but it was noticeably loud.
They have a pretty ingenious elevator system that tries to group riders according to what floor you are going to (there's a panel that will ask you to enter what floor you want and send you to the appropriate elevator - A, B, C, D, etc.).
Also a big plus was the McDonalds (wasn't marked up, which was nice). I'd like to see them add a coffee shop or something so I wouldn't have to walk over to the Starbucks to grab a cup of coffee.