5th and Wine is one of my favorite restaurants here in the valley. I get to feel trendy and upscale in a relaxed, comfortable environment. I have yet to find something on the menu I don't love. Among the best items on the menu (in my personal opinion) are the Seasoned Fries (explained to me as 'crack' fries the first time I visited, because of how awesome they are), bruschetta plates, chicken pesto pasta, and white sangria.
I have almost always had amazing service at 5th and Wine but had to refrain from giving 5 stars because of the service I have had twice with a specific waitress, and sometimes the live music tends to drown out any conversation I would want to have over a glass of wine or dinner.
If you can get there for happy hour there are $5 glasses of wines, $20 bottles, and deals on appetizers.