This is one of the better Home Depot's in Charlotte, at least from my experience. The staff is always around (usually the downfall of these big box DIY chains), friendly, and knowledgable. The store is laid out logically and usually has what I'm looking for.
Best of all, it's convieniently located on South Blvd between Tyvola and Woodlawn, so it's right on my way home from work.
Overall a good store for your home hardware needs!