Clothes Minded is hands down my favorite consignment shop in Pittsburgh.
The owner buys fairly and sells great vintage and name brands for bargains compared to other places in the city. (Cough cough Avalon Exchange) He's always friendly and helpful too.
I've bought multiple ModCloth dresses here for a fraction of the retail price, the jewelry counter always has something that catches my eye, and the clothing racks aren't jammed in the store. You're not fighting for a spot to browse on the rack, you know?
Sometimes I do wish the clothing turnover was a little better; I stop by once every month or so and can usually spot multiple things I remember seeing during my last visit. However, I'm sure it's a store that will catch on more over time.