Local favorite. A tourist must. A college student's best friend.
Brew pubs tend to be either focus entirely on the "brew" (good beer, terrible food, even worse ambience) or on the "pub" (mundane/expected beer, amazing atmosphere.) The Great Dane successfully executes all factors necessary for local college students and alcoholics to call it home, including a killer patio, a traditional rathskeller, and beers to drive from Milwaukee to taste.
Tri pepper beer? Yes, please. Abrikoos, a peachy, girly brew? I'll have 3. The stout is very tasty as well as the healthiest beer according to Men's Health Sept 2010 (thanks to my boyfriend and his roommate for being inefficient and each having a subscription. )
See you next happy hour, you frisky puppy.