2 stars for me.
I love Las Vegas, and consider myself almost a resident there =D I have to say that I was pretty disappointed at Cafe Vettro.
As others have pointed out, decor is great... but then again, now that I think about it, it better be as the place is new. Everything else is mediocre at best. Food was "meh", service was questionable, and price point was unattractive considering food and service qualities.
One thing they DID get right was to ask for my ID when I paid via room charge.. unlike some place over at Vdara as I had a fraudulent charge.
I suggest that you go elsewhere for food... it's a huge casino/hotel, so there are other options.