Very unusual museum located in the heart of the Cultural District. I've visited the Cartoon Museum in London, and I've heard there's one in San Francisco...but as you may realize, you have a long way to travel to visit other cartoon museums.
Keep in mind, the Toonseum is small, but it makes up for that with some very creative exhibits. The gift shop is excellent!
The staff and volunteers are very welcoming, it's a fun place to visit. They also host some great events (for example, I recently attended a book signing at the Toonseum).