We just stayed at the Luxor in the East Tower for two nights. We had booked a room in the pyramid, but when we checked in the desk clerk explained that the only rooms left were directly above the nightclub, and we probably wouldn't get any sleep. The rooms are clean and comfortable with a tasteful Egyptian motif. There is a large bathtub and a separate shower, so both can be used at the same time if necessary. Flat panel television (not much of a channel selection, but that's par for Strip hotels - they want you downstairs playing). The lighted closets built into the television cabinet - which includes an in-room safe - were a nice touch.
The main drawback is how spread out it is. The towers were added after the pyramid was built, and it shows. The path to the tower elevators is long and winding. There are also only two levels to the parking garage, and the bottom level is usually full - which means parking your car out in the summer sun, not fun when you're leaving.
Every employee we met was friendly and helpful. We will definitely consider staying here again.