I am always reluctant to support this American chain, given its reputation for terrible treatment of employees and totally incompetent handling of special orders.
However, I wanted to note this location does sometimes have items not found in the nearby Canadian Tire and Rona stores, but more importantly it seems to be one of the few - if not the only - home improvement big box store in Toronto which is open till midnight. So if you constantly work late or forget something for a project at the last minute, take note. The other Home Depot's in Toronto close at 9, BTW.