As far as Pittsburgh Wine & Spirits stores go, this one is probably the best. That being said, it's so depressing to come to this store after buying wine in New Jersey for years. Sigh. In any event, the staff is generally friendly, and there are some decent tasting notes on the featured wines near the front of the store.
The selection is surprising as well, and I am able to get some of my favorite Napa Valley wines here without special ordering. They don't have everything I'm looking for all of the time, but there are usually at least a few options, even when I'm looking for something specific.