I've been to Comedy Zone probably 6 times since they've opened and I've never had a bad time. They serve food/drinks, but we've only eaten here once. I think if you expect average bar food, you're in luck!
The people here are very friendly and we always have lots of laughs! There are usually 2-3 comedians who come on before the main event, so you get some variety. We've mainly seen random comedians we've never heard of, but they also have big names if you want to pay more... Uncle Joey anyone?!?! He will be making an appearance at the end of the month (who knew!).
On the weekend parking is a pain - just park over by VBGB and walk over, or you can valet in front of Wet Willy's. And we usually eat at VBGB before too.