This is an XXL store with huge selections of everything. My favorite thing is the enormous buffet of prepared foods and spacious eating areas inside & out. The produce is perfect and fresh; you won't see raspberries that are starting to grow mold or aging produce (common in the Bay area branches).
It is a bitch to get to, and I wish it were closer to the popular hotels. But I'm happy Whole Foods even exists in Vegas. Plus, there are lots of familiar and convenient chain stores near by that compensate for the distance: Barnes & Nobel, Target Greatland, etc.