Biggest slice ever versus sketchiest block ever. It's a tough decision.
Big Slice has decent pizza for super cheap -- definitely a key component of an education at Ryerson. Plus they give you a discount if you're a Ryerson student. But I am no longer a student, slaving away overnight at editing suites two blocks down. I can now afford to go elsewhere and not be frightened off by the...interesting array of people who congregate in front of here, whether they're from the Youth Drop-In Centre a couple doors down, or Zanzibar (skeezy strip club).
If it is really late and you live around the corner like I once did, then Big Slice is your place. Otherwise, take it or leave it.