I love everything about Smith's except their Pharmacy on their Lake Mead and Rampart location. I wouldn't go if you have any type of medicine that would be more dangerous than basics.
Otherwise, I go to all their other locations because of my bad experience with that pharmacy. Their Deli's have Boar's Head goods, some Smith's are not staffed accordingly for this, but better than Von's, Albertson's or the smaller selection of Boar's Head at Sprouts.
Prices overall are great as they are in a price war with the other big chains. They lost some money corporate wise due to the merger of Vons and Albertsons but they will bounce back. They were voted Best Las Vegas Food Store by 2 mil LVRJ readers recently.