Don't mind the smell as you walk into the Regional Enterprise building (across from Mellon Square), I suppose that's just par for the course for being open the public all day without providing public restrooms, or do they? I'm not sure but they should encourage use of the facilities a little more.
Moving along, I love this place mainly because of the gal who runs it, she is super friendly and even though I'm not a regular I feel like she always at least pretends to remember me. The americanos are perfect and if you're not feeling like caffeine I'm pretty sure Simpatico is the only place in town offering Ovaltines, iced/hot. They also have a bunch of tasty sandwiches, cookies and smoothies.
If you work downtown skip Starbucks and check it out!