One of my favorite Pittsburgh spots! There are three completely different levels - which means three great atmospheres for you. There is the downstairs, feels like a very standard bar. The middle floor is the "typical restaurant" /dining feel and the upstairs has a very cool, relaxed lounge vibe.
Drinks: If the third floor has space - go up there and ask for Cecil. Not kidding. He's a magician. Everything on the menu is creative, but they can make you just about anything.
Food: Get the Cauliflower, sprouts, mac and cheese, any of the fishes....really I havent had a bad meal there. The hanger steak is great too (get it rare-medium).
This may be a little pricey for some people- but the food is so worth it.