To be honest, I only ever head to this museum for their SMoCA Nights, which are pretty cool if you haven't checked it out.
if you go, break out your hipster gear or be prepared for some tight pants and too-pretty hair. but it's a cool way for local fashion designers, bands and street artists to get some exposure with a crowd that will enjoy their style - it can be a lot of the same faces and artists, though...i feel like once i went to one, i couldn't expect anything different the next time or the time after that.
but! it's a cool way to see the newest exhibits. which are are really innovative. i.e., an entire architecture firm (Eddie Jones) operating out one of the galleries for several weeks - they literally moved the entire office into the museum- and the Celebrity exhibit is really unique, i can't wait to see that.