Pizza Care is rapidly becoming my favorite pizza place in Pittsburgh, mostly because of the flexibility in the menu, including and especially some healthy-ish options. Want a regular pizza? You can have it. Need an on-time order for a large party? They can handle it. Want a crazy level of topping customization? They've yet to mess up one of my orders yet, and I've placed plenty of them.
But what really sets them apart is their insistence that pizza doesn't have to be total junk food. You can swap the crust for something whole wheat or multi-grain (whole wheat options available for hoagie rolls, pasta, and wraps too); there are tons of viable sauce options; they even have low-fat cheese and gluten-free options for pizza crust and pastas.
Over the past year I've been moving more and more of my pizza business to Pizza Care--at this point they're getting well over 90% of my orders (not counting when I'm traveling).
In my opinion, every city should have at least one or two places like this.