Pretty much Cheesecake Factory re-branded for the Venetian/Palazzo.
The Grand Lux is an expansive restaurant decked out in marble and usually a go-to option for most people staying here. The food here is standard American fare with a couple of unique dishes. Portions are pretty big and there is usually something for everyone. The Grand Lux has plenty of seating and I've rarely seen it to be busy.
The menu is huge featuring a wide array of salads, sandwiches, and unique entrees from a variety of cuisines. Alot of dishes (of course the desserts) are ported over from Cheesecake Factory and bumped up a little on the price. I don't really mind CF so Grand Lux is fine with me but there are a lot better places at either resort.