Rooms and bathrooms are large but vey basic. Not a lot of lighting...so it was hard to see in my room...but that's not why you're in Vegas, right? Service was gracious and very helpful.
I had a rental car so access to the strip was easy...but would have been frustrating if no car. Daytime on the strip is much more active, where the Palms is dead during the day. During the summertime...I'd say go to the pool. In the winter...visit the Hammam spa.