I resisted Twenty-Two for a long time because I felt like it wasn't the kind of place where I belonged, but as it turns out, they didn't feel the same way.
I'm your second-hand jeans, wear it cause its comfy, drinking craft beer on a budget kind of gal and from the outside Twenty-Two looked, straight up, too posh for me. But after some goading from Julia S. I sucked it up and gave them a try. Now I look forward to making it a regular staple. They have a wonderful beer selection, both on tap and in bottles (expect to pay about $6 a beer, which isn't terrible). The art is well displayed and interesting. The chairs are comfortable and the atmosphere is conducive to having a long conversation in the way a bar generally may not be.
Oh, and the bathrooms are fabulous. You know, just so you know.