For Indie, Oldie, Classic, Canadian, or Film Festival movies, the TIFF's Bell Lightbox has a rotating choice of movies for everyone at some point. This really is going to be the start of Toronto's Cultural corridor of John Street- perhaps Hooters should start looking for a new location?
The Tiff tower has food, a little curated museum area, and a regular movie theatre set up. There are 3 theatres, but not all have movies all the time. If a movie you want to see is here and at other theatres, this is certainly a destination site. Dress up to come here, or not.
Tickets can be purchased online or at the box office.