Love, love, love this place for brunch. Have been numerous times for brunch and have never had a bad entree. Also really enjoy the unique bread selection with brunch, which includes items like mini coffee cakes and mini scones (all with slightly southwestern flavors).
Having been to Mesa Grill in NYC several times as well, this location does not offer quite the same level of food (as one would expect). Service at the NYC location also tends to be a bit more professional, although the service that I've received in LV has always been exceptionally friendly and attentive so no complaints.