Helton and Wren House are my neighborhood breweries. I live pretty much smack-dab in the middle of both. What's really cool about Helton is that you can see the whole brewery and geek out on all the equipment.
They also recently opened the patio, which is a great spot to hang out and waste away an afternoon.
Anyway...Helton has been brewing great beers from day one. There's a style for everyone. I'm big on IPAs and the house IPA at Helton is great, reminds me of some of the West Coast staples from Knee Deep or Modern Times. My favorite Helton beer however, is the Northeast IPA, which sells out pretty quickly. Get on that if you're lucky enough to be there when it's on tap.
Oh, and growler fills are a smokin' deal. A 32 oz refill is around the same price as a pint (that's for a fill, the new growler will cost a bit extra). Can't beat that price for fresh locally-brewed craft beer.