Definitely helps getting from Mandalay bay to the rest of the strip. It goes either direct to Excalibur, or makes a stop at Luxor (two separate Trams, follow the signs). This is especially helpful if you're wandering (stumbling?) the strip with one of those yummy alcoholic slushies ever so popular in Vegas. Times change on weekends (til midnight i think) so after that a taxi or walking will be your best bet.