First of all, I love the name: if you're going to go with a pun, it had better be a good one, and "Drawn and Quarterly" is perfect for a comics publisher. But the material they put out is truly and consistently top-notch contemporary indie stuff: Seth, Chester Brown, Kevin Huizenga, et al.
Maybe what I respect most about Drawn and Quarterly is that they're uniquely Canadian, without seeming like they do "Can-con" just to fill some quota. Read something like Seth's "Clyde Fans"--a surprisingly compelling story about fan salesmen in southern Ontario--and you'll see what I mean. Everything I've read from Drawn and Quarterly is authentic and unusual.