Could I do all my shopping at Penn Mac? No way.
However, it will always be at least a bi-weekly stop for me because of their amazing selection of Italian imports and fresh cheese. Things I'll always buy here: canned San Marzano tomatoes for homemade sauce, fresh mozzarella, pepperoni, and these awesome little Italian candies called Pocket Coffee.
If you're in Pittsburgh and ever cook Italian food, I recommend a stop!