I prefer Lowe's over Home Depot for the following reasons:
1. Better gardening department including tools, seeds, plants, decorative pots and garden knickknacks.
2. Better organization items such as closet organizing, garage organizing, baskets, wall hanging, kitchen organizing. I'm addicted to organizing and Lowe's has nice decorative items that hold up. Got some awesome wall shelves here to arrange paintings on!
3. During the holidays they have great decorative section, specifically Christmas.
Sometimes it is hard to find an associate and get help, but typically I don't need help anyways because things are easy to find.
Hurray for Lowe's!