Angelos beats out any pan pizza I've ever had. I've been to tons of places in the major midwest cities. They have a great menu selection and the prices aren't that bad either ($2.50 beers, $12-15 large specialty pies)
It's always busy in the dining room, so plan on waiting a few minutes, also parking can be a little dicey if you don't want to walk a block or two.
There's nothing in my new hometown of Columbus that compares to the deliciousness of angelos.
Tip - for an asian inspired twist on a pie, try the seafood pizza.